Basic Information
VIS ID
TVIS44010144
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
54180356/54146444 (Hg38)
End
54180356/54146444 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/3404067; hsa-mir-11401/Downstream/2099076;
Nearest TSS
ENST00000527434/Upstream/76548; ENST00000637049/Downstream/3246;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/24176, chr16-CpG: 19/Downstream/47868
Nearby gene
FTO(+31977) ;
Upstream sequence
CCTTTTCTATGTAATTTTGAAAATTAGGAGGAGATAACTGTCGGACTCAATTCTCCATGTTAAAACCACCTCTCTGGAGTTATATAGTTCTTTCTGAATG
Downstream sequence
TATTAAGGTCATCCTTAGAACGTAAAAGATAATTTTTTGGGTAAATATTCTATGAATAATTTTTAAAATATAATCTTTCTATGGGATACAATTTGATACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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