Basic Information
VIS ID
TVIS44010147
Fusion event
HTLV-1-ASIC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
31795052/33468034 (Hg38)
End
31795052/33468034 (Hg38)
Orient
+
Location type
Intronic
Target gene
ASIC2
Nearest miRNA
hsa-mir-1180/Upstream/1117832; hsa-mir-10226/Downstream/3565711;
Nearest TSS
ENST00000595228/Upstream/175046; ENST00000585093/Downstream/66076;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/174587, chr17-CpG: 46/Downstream/571890
Upstream sequence
aataaatctcttcaaatATTTTACAGCATTTGACCCTTTTCATTGACAGTTATATGCCCTCAGTGGTGGGGAGACTGGGCCAGAGAGCTGGACAGATCTC
Downstream sequence
ATCCAGGACTAAGATGCTCAGACCAGCAGGCTTCTAGACATATCAGATGGCTCTTCCTTGGTTCTCAAGACTGAAGACTCAAAGATATGAATGACAGAGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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