Basic Information
VIS ID
TVIS44010163
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
69343022/71675786 (Hg38)
End
69343022/71675786 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/4594100; hsa-mir-548av/Downstream/1177535;
Nearest TSS
ENST00000575820/Upstream/96830; ENST00000563639/Downstream/106440;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/1244926, chr18-CpG: 225/Downstream/865953
Upstream sequence
ATTGATTACACATAATAAATGTGTAGATGGGCTATTTACTAATGTTAGCTGCTCCACTATATTGATTCTAGCATGTATGATTTGACCCTATGATTATTTG
Downstream sequence
TAAATACCATGCATCAGACAAAAGTTAATTTTAAAGGTATCATTCACTGAGTTTTGTcaatcattatatagaatatttccatagcctatattcccccttg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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