Basic Information
VIS ID
TVIS44010198
Fusion event
HTLV-1-LINC02030 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
55332777/55298749 (Hg38)
End
55332777/55298749 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02030
Nearest miRNA
hsa-let-7g/Upstream/2452197; hsa-mir-12124/Downstream/553743;
Nearest TSS
ENST00000440867/Upstream/2549; ENST00000469484/Downstream/52166;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/672138, chr3-CpG: 24/Downstream/171424
Nearby gene
WNT5A(-166966) ;
Upstream sequence
CATTATGCCTCCGTCCACCCTGAACCCACAGCTTCCAGTGGTAACCATGATCAATAGAGTAGATATACCTCCTCCCAAGCTTTTTCCTTTGTAATAAATG
Downstream sequence
CATATATATGTACACATAAACATGTTTCATTTGGAAAATATTGTGTTTCCACACAAATGGTGTCACAATATGTGCATTGTCTGCAAACTAGCTTTGCTTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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