Basic Information
VIS ID
TVIS44010212
Fusion event
HTLV-1-LOC107986107 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
104263500/104544656 (Hg38)
End
104263500/104544656 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107986107
Nearest miRNA
hsa-let-7g/Upstream/1020540; hsa-mir-12124/Downstream/5058172;
Nearest TSS
ENST00000440867/Upstream/1870743; ENST00000470756/Downstream/822253;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/2694454, chr3-CpG: 32/Downstream/809029
Nearby gene
MIR548A3(No orient, 317395)
Upstream sequence
ttctaattactcgtgcatgcagcccccagtcacatacccgctgcttgctcaatcgatcacgaccatcccaagcggacccccttagagttgtgagccctta
Downstream sequence
aaagggacaggaattgctcactgggggagcttggttgttgaagacgtgagtcttgccaaagctcgtggccagataaagcccttccttctttaactcgtgt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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