Basic Information
VIS ID
TVIS44010254
Fusion event
HTLV-1-SSBP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q14.1
Reference genome
End
80993870/81698051 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6797-3p ; hsa-mir-6076 ; hsa-mir-4722-5p ; hsa-mir-7854-3p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4649-3p ; hsa-mir-1247-3p ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6499-3p ; hsa-mir-4537 ; hsa-mir-493-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-25-5p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-139-3p ; hsa-mir-6087 ; hsa-mir-5091 ; hsa-mir-3192-5p ; hsa-mir-3149 ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-6832-5p ; hsa-mir-1273f ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-4735-5p ; hsa-mir-7851-3p ; hsa-mir-619-3p ; hsa-mir-590-3p ; hsa-mir-4443 ; hsa-mir-1299 ; hsa-mir-3191-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-7160-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6128 ; hsa-mir-875-3p ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-518c-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-216b-5p ; hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-4772-3p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-4485-5p ; hsa-mir-7108-3p ; hsa-mir-4258 ; hsa-mir-6513-3p ; hsa-mir-8062 ; hsa-mir-3165 ; hsa-mir-363-5p ; hsa-mir-3656 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4683 ; hsa-mir-6745 ; hsa-mir-6888-5p ; hsa-mir-1227-3p ; hsa-mir-1262 ; hsa-mir-1273g-3p ; hsa-mir-4252 ; hsa-mir-451b ; hsa-mir-4696 ; hsa-mir-4701-3p ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-542-3p ; hsa-mir-550b-2-5p ; hsa-mir-6501-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-766-3p ; hsa-mir-7703
Nearest miRNA
hsa-mir-10397/Upstream/8819388; hsa-mir-103a-1/Downstream/1142104;
Nearest cancer related gene
SSBP2(TSG, No orient, 0)
Upstream sequence
ACATATTCTTTTGAAAAATAACTTCTTTACACTGTGTTTTATATCCCAACTAATTTTATATTCAATTTCTTTTTTTAAGACACTATCTCCTAAAATGTTA
Downstream sequence
AAGATGATACTGGGAAATTTATGTGACCATTTAAAATAATCAGACTATGACTAACATAGAATATAAATGAACTACAAAGAAAATACACTGAAAGTAAAAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate