Basic Information
VIS ID
TVIS44010259
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
107842234/108506533 (Hg38)
End
107842234/108506533 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA5F
Nearest miRNA
hsa-mir-10397/Upstream/7689968; hsa-mir-103a-1/Downstream/2007296;
Nearest TSS
ENST00000502646/Upstream/124435; ENST00000513676/Downstream/221727;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/123933, chr5-CpG: 34/Downstream/221501
Nearby gene
FBXL17(-124435) ;
Upstream sequence
aaactattctgtaagtcactgtcagtttctagaaagcaaaactgctcattttcccattatacttaaaacatttcatttgttcctcatctctttcaggata
Downstream sequence
aaattcaaattccttgatatggcaataacaagcacttggtggtttggctccagattccctttAAAGCTTGCATTTCattcatttattaagcaaagaacat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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