Basic Information
VIS ID
TVIS44010275
Fusion event
HTLV-1-LOC105377865 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
78983190/78273473 (Hg38)
End
78983190/78273473 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105377865
Nearest miRNA
hsa-mir-10398/Upstream/2845000; hsa-mir-10524/Downstream/265790;
Nearest TSS
ENST00000381078/Upstream/582815; ENST00000607739/Downstream/332563;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/622846, chr6-CpG: 46/Downstream/593968
Nearby gene
MEI4(No orient, 348714)
Upstream sequence
TAGCATATATCTCATTAATACAATTATGATATCTTGAACTGTGCAGGACAAACAGTCCTATTTTTATTATATGAAATAGTCTTTGTAAGTATCTAATTAC
Downstream sequence
CTACTTCCCTTGATAACACTGAAAAAAGACCTTGAATCTTAAAAATTTCCACTTTAAAGTAAGTATAGTGCAAGGACAGATCAATGTAGTACTATGTTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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