Basic Information
VIS ID
TVIS44010284
Fusion event
HTLV-1-SNX13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
17956910/17917287 (Hg38)
End
17956910/17917287 (Hg38)
Orient
-
Location type
Intronic
Target gene
SNX13
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-136-5p ; hsa-mir-1226-3p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-124-3p ; hsa-mir-506-3p
Nearest miRNA
hsa-mir-339/Upstream/10850242; hsa-mir-10399/Downstream/209933;
Nearest TSS
ENST00000635602/Upstream/17039; ENST00000455069/Downstream/23144;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/617810, chr7-CpG: 82/Downstream/22864
Upstream sequence
acacacccacagccaacatcatcataaatgggcaaaagctggaagcattcccctaagaactggagcaaaacaaggatgtccactcttgccactcctattt
Downstream sequence
aacatagtaccagaagtcttagagcaatccggcaaggaaaagaaagaaaacgcatccaaatagaaaaagaagaagtcaaataatttccctttgctgacca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate