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TVIS44010294
Basic Information
VIS ID
TVIS44010294
Fusion event
HTLV-1-ZNF277 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
111889438/112249383 (Hg38)
End
111889438/112249383 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF277
miRNAs that regulate target gene
hsa-mir-7151-3p
;
hsa-mir-6807-5p
;
hsa-mir-5095
;
hsa-mir-550a-5p
;
hsa-mir-550a-3-5p
;
hsa-mir-1271-3p
;
hsa-mir-661
;
hsa-mir-3116
;
hsa-mir-1254
;
hsa-mir-6504-5p
;
hsa-mir-3064-5p
;
hsa-mir-4438
;
hsa-mir-6788-5p
;
hsa-mir-7113-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-4325
;
hsa-mir-30c-1-3p
;
hsa-mir-7703
;
hsa-mir-500a-3p
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-6878-5p
;
hsa-mir-767-5p
;
hsa-mir-4524a-3p
;
hsa-mir-3192-5p
;
hsa-mir-766-3p
;
hsa-mir-6849-3p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-367-3p
;
hsa-mir-363-3p
;
hsa-mir-32-5p
;
hsa-mir-25-3p
;
hsa-mir-508-5p
;
hsa-mir-129-5p
;
hsa-mir-8055
;
hsa-mir-1273f
;
hsa-mir-4708-5p
;
hsa-mir-6088
;
hsa-mir-4770
;
hsa-mir-143-3p
;
hsa-mir-8087
;
hsa-mir-7161-5p
;
hsa-mir-548u
;
hsa-mir-2355-3p
;
hsa-mir-4646-3p
;
hsa-mir-676-3p
;
hsa-mir-501-5p
;
hsa-mir-1224-5p
;
hsa-mir-1294
;
hsa-mir-4316
;
hsa-mir-4751
;
hsa-mir-4677-3p
;
hsa-mir-1197
;
hsa-mir-1290
;
hsa-mir-3167
;
hsa-mir-5004-3p
;
hsa-mir-876-5p
Nearest miRNA
hsa-mir-10525/Upstream/9777852; hsa-mir-10399/Downstream/2403962;
Nearest TSS
ENST00000635602/Upstream/42682;
ENST00000421864/Downstream/88345;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/42551
,
chr7-CpG: 92/Downstream/142037
Upstream sequence
AACCAATAAATACATAGGTCCAATGAACAAAATAAGTAATAAAATATTGGCTTTAATACTCAAAATTAGGGGTTCCCTCTTAAACTGTTAGTAGATGTGA
Downstream sequence
CTTTGTACTGTGTTAAATGAGCCATTTGATCCCTTTCATGCCTCGGGGATTGGAAGAGAGAGGTCTGCTTAGTAGATACTTAAACCAGATAGCTGTGTAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL188
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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