Basic Information
VIS ID
TVIS44010298
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.2
Reference genome
GRCh37/hg19
Start
153315048/153617963 (Hg38)
End
153315048/153617963 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/2184324; hsa-mir-153-2/Downstream/3956373;
Nearest TSS
ENST00000635602/Upstream/204000; ENST00000462622/Downstream/269134;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/691743, chr7-CpG: 87/Downstream/130116
Nearby gene
LINC01287(No orient, 205729)
Upstream sequence
CCTTATCCTTTTCCAGCTTATCCTTACTCTGGCTGGATGGGACATATCCCAGAGGTAGGCCTTATTTGGAAAGAGAAGAATGGTTCCTTAAGTGATGAAT
Downstream sequence
GGCTCGCTGGACCAGGACTCCTGATAAATGATGCCATAGGAGTATTTTATTGTACAAACTACTCCTGAGTACATGGTTGGATAATAAGATCTAACAATTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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