Basic Information
VIS ID
TVIS44010326
Fusion event
HTLV-1-PTCSC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
100493448/97731166 (Hg38)
End
100493448/97731166 (Hg38)
Orient
-
Location type
Intronic
Target gene
PTCSC2
Nearest miRNA
hsa-let-7a-1/Upstream/367485; hsa-mir-12126/Downstream/497983;
Nearest TSS
ENST00000422679/Upstream/33809; ENST00000562653/Downstream/12042;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/33673, chr9-CpG: 45/Downstream/10105
Nearby gene
XPA(-33757) ;
Upstream sequence
cattcattcaacaaatttttttctagctttattgaagtatgattgagaaataaaaattatatatattttgggtatataacatgatgttttgatatatata
Downstream sequence
cacattggcaaatgattactacagtaatgctaatagcatattcattaccttacatagttactgtgtgtgtgtgtgtgtatgttgtgtgcatgtgagataa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate