Basic Information
VIS ID
TVIS44010329
Fusion event
HTLV-1-DCAF8L2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
27563746/27545629 (Hg38)
End
27563746/27545629 (Hg38)
Orient
+
Location type
Intronic
Target gene
DCAF8L2
Nearest miRNA
hsa-mir-23c/Upstream/7528442; hsa-let-7f-2/Downstream/949926;
Nearest TSS
ENST00000429181/Upstream/82288; ENST00000580017/Downstream/44753;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/987574, chrX-CpG: 28/Downstream/318208
Upstream sequence
taattccctatgctgggggaggaacctggtaggaggtgattagatcatcggagcggatttcccccttgctgttctcatcatagggagtaagttcttgtga
Downstream sequence
cagtgagtaagttctcatgagatctgtattagtctgttttgacactgctataaagaaattcctgagactgggtaatttataaaggaaagaggtttaattg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate