Basic Information
VIS ID
TVIS44010343
Fusion event
HTLV-1-LOC105373369 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
GRCh37/hg19
Start
151248480/152080008 (Hg38)
End
151248480/152080008 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRAXE ; FRAXF
Target gene
LOC105373369
Nearest miRNA
hsa-let-7f-2/Upstream/120296; hsa-mir-105-1/Downstream/312211;
Nearest TSS
ENST00000429181/Upstream/105328; ENST00000453915/Downstream/58502;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/105109, chrX-CpG: 68/Downstream/557746
Nearby gene
MAGEA10-MAGEA5(-34041) ;
Upstream sequence
tgcatgtagaaaatctcaaagaatcaacaaaaaagcctttgaaagtaataagtgattattgcaaggttgcagaatatgtactaaagtcaatttattttct
Downstream sequence
atatactagcaatgagcaattagaatttgaaattcaaaacacaacactatttaaatttcaaccaaaatattaaatacttaggcacaaatctaagaaaata
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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