Basic Information
VIS ID
TVIS44010344
Fusion event
HTLV-1-chrY integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
13460755/11305079 (Hg38)
End
13460755/11305079 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-2/Upstream/6698851; hsa-mir-12120/Downstream/2174098;
Nearest TSS
ENST00000430575/Upstream/1394281; ENST00000417071/Downstream/1357255;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/90037, chrY-CpG: 92/Downstream/1836
Nearby gene
DUX4L17(+1839) ;
Upstream sequence
acacagagcctagacaagagtcccatcacctgggtgatcagtgcagaaatatgtcacaatgcccctataggccgatcgaagacaagagtccttcacctgg
Downstream sequence
gtgatcagtgcagaaatatgtcacaatgcccccttaggcagagcctagataaaagccccatcacctggatgatcagtgcagagttatgtcacaaattccc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate