Basic Information
VIS ID
TVIS44010377
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
14717346/14814029 (Hg38)
End
14717346/14814029 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA17A
Nearest miRNA
hsa-mir-1253/Upstream/1270383; hsa-mir-10226/Downstream/437598;
Nearest TSS
ENST00000595228/Upstream/33826; ENST00000445035/Downstream/20609;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/468625, chr17-CpG: 77/Downstream/446584
Nearby gene
CDRT7(+216946) ;
Upstream sequence
caagttctgccggcgcagcactacaaactcttctctgccattcagggagccacggtctttccttccccaatgtgatctgaggctaagctctagggtagat
Downstream sequence
gcgggtcttgtccttggttgctctatctcatccctaggggtagaggatattccttatatgttctattcctatttagagttctcatcacctccttccagac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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