Basic Information
VIS ID
TVIS44010393
Fusion event
HTLV-1-LINC02755 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
29360179/29338632 (Hg38)
End
29360179/29338632 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02755
Nearest miRNA
hsa-mir-210/Upstream/861084; hsa-let-7a-2/Downstream/5603205;
Nearest TSS
ENST00000527297/Upstream/178676; ENST00000527727/Downstream/11717;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1227958, chr11-CpG: 25/Downstream/677493
Nearby gene
LINC01616(No orient, 641489)
Upstream sequence
atcatggtgggaggtgaagggggagcaaatacatcacatggccagagcaggagcaagacagagacaggagaggagccacacacttttaaacaaccagatc
Downstream sequence
ttgcaagaactcactcactaccatgacaacagcaccaagggaatggggctaaaccattcctgagaaatccacctccatgatccaatcacctcccaccagg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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