Basic Information
VIS ID
TVIS44010398
Fusion event
HTLV-1-C16orf47 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
73595599/73561700 (Hg38)
End
73595599/73561700 (Hg38)
Orient
+
Location type
Intronic
Target gene
C16orf47
Nearest miRNA
hsa-mir-1225/Upstream/3531278; hsa-mir-11401/Downstream/3307236;
Nearest TSS
ENST00000527434/Upstream/17759; ENST00000637695/Downstream/232379;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/494808, chr16-CpG: 74/Downstream/734935
Nearby gene
LINC01568(No orient, 140304)
Upstream sequence
TATCATAAATTTGGAATTTTTCAAGTTCAAAATAACTAGGGTTTATTATTCTTATACTTTACTGAAGACAACTAACTCTCTCCCAGTGATTTCTTTCTCT
Downstream sequence
TTTCCCTTCTGATTACAACAAAAATCCAGCTACCTAAAATAGGCTTATTCCTCAAAAGGAAACAAAACTGCCGAGTTCTATGACAATAATACTAATCAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate