Basic Information
VIS ID
TVIS44010402
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
61989398/62529020 (Hg38)
End
61989398/62529020 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/5123930; hsa-mir-10399/Downstream/1092070;
Nearest TSS
ENST00000635602/Upstream/5078843; ENST00000418297/Downstream/525411;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/148123, chr7-CpG: 49/Downstream/525117
Upstream sequence
ttgaacctttcttttgatagagcagtattgaaattctccttttgtagaatctgcttgtggatatttggagctatttgcagccttcattggaaatgggata
Downstream sequence
tttacaaataaaaactagacggaagcattctcagaaactgctttgtgaggtggacattcgactcacagtgttgaaactttcttttgatagagcagttttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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