Basic Information
VIS ID
TVIS44010415
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
48560542/47178818 (Hg38)
End
48560542/47178818 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA10G
Nearest miRNA
hsa-mir-1265/Upstream/2014730; hsa-mir-107/Downstream/1806694;
Nearest TSS
ENST00000439456/Upstream/238236; ENST00000580279/Downstream/121568;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/267049, chr10-CpG: 93/Downstream/121223
Nearby gene
GDF10(-121404) ;
Upstream sequence
ATGGCCAAATTGGAAAAAGAGTCACCTACAATTGACTCAGCTAGCCAGCTCACAGGGCTGCAGAACTGTACTCATCTGCTAACAGCCCTATAACAATATC
Downstream sequence
CTCTATGAAACACTTTGTGTGTTTTCTTGTACCTTTCCAATTACCAgaggttgattttgctctacccattttacagaggaagaaactgaggtgcatggac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate