Basic Information
VIS ID
TVIS44010423
Fusion event
HTLV-1-TTC17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
43424792/43403242 (Hg38)
End
43424792/43403242 (Hg38)
Orient
-
Location type
Intronic
Target gene
TTC17
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-1343/Upstream/7393038; hsa-let-7a-2/Downstream/156414;
Nearest TSS
ENST00000527297/Upstream/5209; ENST00000530483/Downstream/810;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/43752, chr11-CpG: 20/Downstream/119043
Upstream sequence
AGGGAAGAAGGGGGATGTTTAGAAATGAAATAGATTGAAACCCAATACACCTTTTGGACTTTTTGATGGTCTCAAGACCGATCATTTGAAGGAGTGTAGC
Downstream sequence
TTCCAATAGTCTATATTCATAAAATTGTATCACCACTATATAGTGAAAGAATCCATTCCTGTTCACAAAGACCTAGAGCTACAAATTCGTCATATTCATT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate