Basic Information
VIS ID
TVIS44010459
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
71917695/71690565 (Hg38)
End
71917695/71690565 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2E
Nearest miRNA
hsa-mir-1285-2/Upstream/1437560; hsa-mir-10b/Downstream/3400247;
Nearest TSS
ENST00000437798/Upstream/79786; ENST00000498749/Downstream/452519;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/129798, chr2-CpG: 18/Downstream/95155
Nearby gene
DYSF(+3802) ;
Upstream sequence
tccccaggtctctttccctggcgctgttctcgtattgtatggctcctaggcaccctcacctgccccactttctctgccttctacaggtgaatgaacccgg
Downstream sequence
aatccctcactgtagcccagtttctcccctccgctgcaggcgccttagtgtactgcttacgcactggcactatgaactcaaaccctcccactcaaagtct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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