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TVIS44010481
Basic Information
VIS ID
TVIS44010481
Fusion event
HTLV-1-ADD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
2905883/2904156 (Hg38)
End
2905883/2904156 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADD1
miRNAs that regulate target gene
hsa-mir-24-3p
;
hsa-mir-221-3p
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-513a-5p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-4684-5p
;
hsa-mir-6868-3p
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-3143
;
hsa-mir-27a-5p
;
hsa-mir-942-5p
;
hsa-mir-520f-5p
;
hsa-mir-1248
;
hsa-mir-1237-3p
;
hsa-mir-660-3p
;
hsa-mir-543
;
hsa-mir-222-5p
;
hsa-mir-298
;
hsa-mir-3158-5p
;
hsa-mir-320a
;
hsa-mir-320b
;
hsa-mir-320c
;
hsa-mir-320d
;
hsa-mir-33b-3p
;
hsa-mir-3614-3p
;
hsa-mir-3619-3p
;
hsa-mir-371a-3p
;
hsa-mir-371b-3p
;
hsa-mir-4429
;
hsa-mir-4473
;
hsa-mir-4671-3p
;
hsa-mir-4724-3p
;
hsa-mir-515-3p
;
hsa-mir-519e-3p
;
hsa-mir-591
;
hsa-mir-6512-3p
;
hsa-mir-6720-5p
;
hsa-mir-6849-3p
;
hsa-mir-193b-5p
;
hsa-mir-3074-5p
;
hsa-mir-3170
;
hsa-mir-4722-3p
;
hsa-mir-4731-5p
;
hsa-mir-6727-3p
;
hsa-mir-6743-3p
;
hsa-mir-6747-3p
;
hsa-mir-6855-5p
;
hsa-mir-7152-5p
;
hsa-mir-7155-5p
Nearest miRNA
hsa-mir-4800/Upstream/654000; hsa-mir-12113/Downstream/3019119;
Nearest TSS
ENST00000502981/Upstream/5725;
ENST00000536078/Downstream/508;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/59625
,
chr4-CpG: 17/Downstream/22170
Upstream sequence
AAAAGTCTATTAAGTATGTTGATGAATATAACCTGCACAGTGGCTGGCAGCAAGTAAACCCTGTTTGGGTGTTCAACtttaattttttgttgaaatatgt
Downstream sequence
aagcaggagagtgcacctaccgcaagtgttcagtttgttcatttttaaaaactgaaccccctgtataaccagcagtcaataagagcaacggtagcagcac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL73
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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