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TVIS44010482
Basic Information
VIS ID
TVIS44010482
Fusion event
HTLV-1-YTHDC1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
69199909/68334191 (Hg38)
End
69199909/68334191 (Hg38)
Orient
-
Location type
Intronic
Target gene
YTHDC1
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-103a-3p
;
hsa-mir-93-5p
;
hsa-mir-19b-3p
;
hsa-mir-16-5p
;
hsa-mir-20a-3p
;
hsa-mir-100-5p
;
hsa-let-7b-5p
;
hsa-mir-590-3p
;
hsa-mir-511-3p
;
hsa-mir-607
;
hsa-mir-6715b-3p
;
hsa-mir-889-3p
;
hsa-mir-5583-3p
;
hsa-mir-4517
;
hsa-mir-2681-5p
;
hsa-mir-4524b-5p
;
hsa-mir-4524a-5p
;
hsa-mir-4310
;
hsa-mir-7157-5p
;
hsa-mir-646
;
hsa-mir-4724-5p
;
hsa-mir-503-5p
;
hsa-mir-6838-5p
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-195-5p
;
hsa-mir-107
;
hsa-mir-6738-3p
;
hsa-mir-4727-5p
;
hsa-mir-5001-3p
;
hsa-mir-3189-5p
;
hsa-mir-4758-3p
;
hsa-mir-5699-5p
;
hsa-mir-18a-3p
;
hsa-mir-324-3p
;
hsa-mir-1913
;
hsa-mir-1207-3p
;
hsa-mir-95-5p
;
hsa-mir-4272
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-548n
;
hsa-mir-143-5p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6499-3p
;
hsa-mir-4518
;
hsa-mir-1266-5p
;
hsa-mir-3664-3p
;
hsa-mir-5693
;
hsa-mir-764
;
hsa-mir-4650-5p
;
hsa-mir-1972
;
hsa-mir-4733-5p
;
hsa-mir-649
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-6739-3p
;
hsa-mir-4677-5p
;
hsa-mir-7156-5p
;
hsa-mir-4273
;
hsa-mir-6514-3p
;
hsa-mir-22-5p
;
hsa-mir-2116-5p
;
hsa-mir-550a-5p
;
hsa-mir-550a-3-5p
;
hsa-mir-1271-3p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-627-3p
;
hsa-mir-519e-3p
;
hsa-mir-515-3p
;
hsa-mir-33b-3p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-548s
;
hsa-mir-3926
;
hsa-mir-4786-5p
;
hsa-mir-3190-5p
;
hsa-mir-6849-3p
;
hsa-mir-4781-3p
Nearest miRNA
hsa-mir-12113/Upstream/2057263; hsa-mir-1243/Downstream/8239377;
Nearest TSS
ENST00000502981/Upstream/4118;
ENST00000510647/Downstream/4221;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/151472
,
chr4-CpG: 52/Downstream/15395
Upstream sequence
TAAGAACCAGTCCCAAGCTTAATTTGGAACTTTGTAAGCATATACATGAGGACTTGAAATGGAATTCAGCTCTCCTATCTGTTTATTTTTATCTTAGTTT
Downstream sequence
TACCATGATAAGCTCCTTTTACTTTTCAGCTTAGAGATAAGGGAATAGGAAGAAAAAAATGCATATACTTATTTTTATATAAACAATGGAAAGCTGAAAa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL73
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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