VISDB Viral Integration Site DataBase

VIS ID

TVIS44010500

Fusion event

HTLV-1-MTO1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

q13

Reference genome

Start

End

74179210/73469487 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-100-5p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-7641 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-4695-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-5693 ; hsa-mir-4742-3p ; hsa-mir-205-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-8055 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-4790-5p ; hsa-mir-4524a-3p ; hsa-mir-4315 ; hsa-mir-5007-5p ; hsa-mir-6787-3p ; hsa-mir-6736-3p ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-891a-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-4772-3p ; hsa-mir-660-3p ; hsa-mir-216a-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-4438 ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-431-5p ; hsa-mir-3194-3p ; hsa-mir-129-5p ; hsa-mir-498 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-132-3p ; hsa-mir-212-3p

Nearest miRNA

hsa-mir-10398/Upstream/501734; hsa-mir-10524/Downstream/1958920;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/7341, chr6-CpG: 135/Downstream/50752

Upstream sequence

gctgaggcgggcggatcactgaggtcaggagtttgagactagcctggccaacatggtgaacctgtctctactaaaaataaaaaaattagctgggcgtggt

Downstream sequence

ggcatgcacctgtaatcccagctactcaggaggctgaggcaagagaatcgcttgaacccaggaggcggaggttgcagtgagccgagatcgtgccactgca