Basic Information
VIS ID
TVIS44010596
Fusion event
HTLV-1-LINC01952 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
GRCh37/hg19
Start
44888396/44848797 (Hg38)
End
44888396/44848797 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7D
Target gene
LINC01952
Nearest miRNA
hsa-mir-1183/Upstream/737885; hsa-mir-10399/Downstream/32951;
Nearest TSS
ENST00000635602/Upstream/381; ENST00000450016/Downstream/262;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/326, chr7-CpG: 124/Downstream/35647
Nearby gene
H2AFV(-671) ;
Upstream sequence
gcttgaaccccggaggcggaggttgcagtgagccgagatcgcgccactgcactccagctgggcgacgcatcgtctcaaaacaaacaaacaaaaacaaaag
Downstream sequence
ctatcaattggctacatattgttatttgtatgacaaattcTTTTTCCTTTTTTAGAGATGGAGTCctgggactacaggcgcgcgccccaatgcccagcta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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