Basic Information
VIS ID
TVIS44010599
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
68977058/69209591 (Hg38)
End
68977058/69209591 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA11H ; FRA11A
Nearest miRNA
hsa-mir-10392/Upstream/126333; hsa-let-7a-2/Downstream/1074364;
Nearest TSS
ENST00000527297/Upstream/38027; ENST00000540760/Downstream/84547;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/52102, chr11-CpG: 26/Downstream/167468
Nearby gene
LOC338694(No orient, 38028)
Upstream sequence
TGGGTCGCTGTCTTTATTGTCTTCCTCAACATCTTCCATGGGAAAGGCCAATGGCTTGAAACAGGATTGACGAGACACCCGGGGCCTGCTCCACACCCGT
Downstream sequence
GGGCTCCTGGGCGTGCACCCAAGAGCCTCCACCCCTGAATGGCTGGCATCCAGGTGGGCTTCCCATAAGGAGCCCCCTTCTGCGGGCCTGGGAGGGTGGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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