Basic Information
VIS ID
TVIS44010603
Fusion event
HTLV-1-LOC101927967 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
78223783/77996657 (Hg38)
End
78223783/77996657 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA2S
Target gene
LOC101927967
Nearest miRNA
hsa-mir-1285-2/Upstream/2905743; hsa-mir-10b/Downstream/1652637;
Nearest TSS
ENST00000437798/Upstream/80723; ENST00000439259/Downstream/92073;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2285644, chr2-CpG: 32/Downstream/996409
Upstream sequence
cctcccaaaatctatatgaaactttttcacctggattcctaagaagcctttctttttcctcaattgtcacaaagtcTTATTTTAACATATATTTTAACCA
Downstream sequence
CTAATGAGCACAATTTGATCAAATTTTTATCAAGCTACTTGTGAAACAGATTTATAAATGTATTGGTTTCTGGTCCTTTCTCCACTACTCATTCAACTCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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