Basic Information
VIS ID
TVIS44010618
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
43950622/43446470 (Hg38)
End
43950622/43446470 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/1095265; hsa-let-7e/Downstream/1207216;
Nearest TSS
ENST00000633603/Upstream/31558; ENST00000600154/Downstream/17493;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/31495, chr19-CpG: 108/Downstream/16625
Nearby gene
LYPD3(-14324) ;
Upstream sequence
ggggtttcaccatgttggccatgctggtctcgaaatcctgacctcatgatctgcctgcctcagcctcccaaagtgctgggattacagtcatgagccaaca
Downstream sequence
cgcctggccGGACTAAGCACTTTCACCTTTATTCTTTTCTGTCTCCAAACTCATCCACAATCTCACCCAGCTTGGACTCACCCCTGGCAGTTCATCTCCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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