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VISDB
Viral Integration Site DataBase
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TVIS44010673
Basic Information
VIS ID
TVIS44010673
Fusion event
HTLV-1-CGNL1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
57707130/57414932 (Hg38)
End
57707130/57414932 (Hg38)
Orient
-
Location type
Intronic
Target gene
CGNL1
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-744-5p
;
hsa-mir-130b-5p
;
hsa-mir-125a-5p
;
hsa-mir-195-5p
;
hsa-mir-1273h-5p
;
hsa-mir-149-3p
;
hsa-mir-1827
;
hsa-mir-3065-3p
;
hsa-mir-30b-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-30c-2-3p
;
hsa-mir-3122
;
hsa-mir-3165
;
hsa-mir-340-3p
;
hsa-mir-3613-3p
;
hsa-mir-3622a-3p
;
hsa-mir-3622b-3p
;
hsa-mir-3665
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-383-3p
;
hsa-mir-3913-5p
;
hsa-mir-3929
;
hsa-mir-4293
;
hsa-mir-4419b
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4478
;
hsa-mir-450a-1-3p
;
hsa-mir-4649-3p
;
hsa-mir-4684-5p
;
hsa-mir-4728-5p
;
hsa-mir-4736
;
hsa-mir-4768-3p
;
hsa-mir-485-5p
;
hsa-mir-544b
;
hsa-mir-6513-5p
;
hsa-mir-665
;
hsa-mir-6765-3p
;
hsa-mir-6771-3p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6787-3p
;
hsa-mir-6788-5p
;
hsa-mir-6799-5p
;
hsa-mir-6808-5p
;
hsa-mir-6827-3p
;
hsa-mir-6849-3p
;
hsa-mir-6883-5p
;
hsa-mir-6884-5p
;
hsa-mir-6893-5p
;
hsa-mir-7106-5p
;
hsa-mir-7160-5p
;
hsa-mir-7162-3p
;
hsa-mir-887-5p
;
hsa-mir-940
Nearest miRNA
hsa-mir-10393/Upstream/2041898; hsa-mir-11181/Downstream/1756251;
Nearest TSS
ENST00000557528/Upstream/37786;
ENST00000621477/Downstream/63397;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/38102
,
chr15-CpG: 47/Downstream/176868
Upstream sequence
cagcctgctgatctgtttggctcctgaactctcatatattgcattgtctatgtttccGAAGTTGtagtggttaaggacacaggctttgggggtgagagag
Downstream sequence
aatgggcataaatcccattccaccacttagtgggttgtgtggttttgggtaaAGGCACAATGAAGAATCTTCTGGGGCATTTCACGGAGCAGATGAATGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL18
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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