Basic Information
VIS ID
TVIS44010701
Fusion event
HTLV-1-PRRG4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
End
32873478/32851932 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-940 ; hsa-mir-1827 ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-130a-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-520g-3p ; hsa-mir-518a-5p ; hsa-mir-520h ; hsa-mir-519a-3p ; hsa-mir-527 ; hsa-mir-583 ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-3159 ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-511-3p ; hsa-mir-4768-3p ; hsa-mir-129-1-3p ; hsa-mir-129-2-3p ; hsa-mir-4687-5p ; hsa-mir-6779-3p ; hsa-mir-539-5p ; hsa-mir-224-5p ; hsa-mir-30c-2-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-887-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6788-5p ; hsa-mir-1273h-5p ; hsa-mir-3177-5p ; hsa-mir-4719 ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-429 ; hsa-mir-1229-5p ; hsa-mir-7703 ; hsa-mir-500a-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-3132 ; hsa-mir-197-5p ; hsa-mir-661 ; hsa-mir-767-5p ; hsa-mir-6861-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6742-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-6501-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-508-5p ; hsa-mir-4717-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-4279 ; hsa-mir-6868-3p ; hsa-mir-6740-3p ; hsa-mir-4778-3p ; hsa-mir-942-5p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-6513-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-6875-3p ; hsa-mir-6809-3p ; hsa-mir-4753-3p ; hsa-mir-452-3p ; hsa-mir-627-3p ; hsa-mir-130b-5p ; hsa-mir-205-5p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-6895-5p ; hsa-mir-1972 ; hsa-mir-5693 ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-5582-5p ; hsa-mir-665 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-4649-3p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-500a-5p ; hsa-mir-1305 ; hsa-mir-6083 ; hsa-mir-511-5p ; hsa-mir-6830-3p ; hsa-mir-7151-5p ; hsa-mir-5571-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-6509-3p ; hsa-mir-6776-5p ; hsa-mir-181a-2-3p ; hsa-mir-483-3p
Nearest miRNA
hsa-mir-210/Upstream/4374384; hsa-let-7a-2/Downstream/2089905;
Upstream sequence
gcatgcaatgtgaaataagcacatcatggagaatggcttatccatcccctatgcatttTAATTATTTCATTAGCCATAACTATAGGAGGTTAATGTATGT
Downstream sequence
ATAGATACTTTATAAATAGCCTAAATAGATTGATTTATTAATGTCTAAATCATAATTTGTACTTCACAAGTGAGAAAGGAAAACCATAGGTTTAAGACCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate