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TVIS44010716
Basic Information
VIS ID
TVIS44010716
Fusion event
HTLV-1-CLCC1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
109483027/108940405 (Hg38)
End
109483027/108940405 (Hg38)
Orient
-
Location type
Intronic
Target gene
CLCC1
miRNAs that regulate target gene
hsa-mir-615-3p
;
hsa-mir-15a-5p
;
hsa-mir-6516-5p
;
hsa-mir-455-3p
;
hsa-mir-6880-5p
;
hsa-mir-6499-3p
;
hsa-mir-508-3p
;
hsa-mir-6086
;
hsa-mir-377-5p
;
hsa-mir-4537
;
hsa-mir-5186
;
hsa-mir-3192-5p
;
hsa-mir-7851-3p
;
hsa-mir-490-3p
;
hsa-mir-7856-5p
;
hsa-mir-3658
;
hsa-mir-548s
;
hsa-mir-3926
;
hsa-mir-6128
;
hsa-mir-4307
;
hsa-mir-619-3p
;
hsa-mir-323a-3p
;
hsa-mir-33a-3p
;
hsa-mir-5197-5p
;
hsa-mir-649
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-769-5p
;
hsa-mir-4786-5p
;
hsa-mir-3190-5p
;
hsa-mir-6849-3p
;
hsa-mir-665
;
hsa-mir-887-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-7160-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-890
;
hsa-mir-34b-3p
;
hsa-mir-30e-5p
;
hsa-mir-30d-5p
;
hsa-mir-30c-5p
;
hsa-mir-30a-5p
;
hsa-mir-30b-5p
;
hsa-mir-181d-5p
;
hsa-mir-181c-5p
;
hsa-mir-181b-5p
;
hsa-mir-181a-5p
;
hsa-mir-3675-3p
;
hsa-mir-4293
;
hsa-mir-4684-5p
;
hsa-mir-6771-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1043101; hsa-mir-11399/Downstream/658488;
Nearest TSS
ENST00000473358/Upstream/26028;
ENST00000473828/Downstream/3122;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/62989
,
chr1-CpG: 68/Downstream/22654
Upstream sequence
TTCATCTTATGTCCAAAATCATGTTTTAAAAATCCATTCAAATTATACATGTTTTATGCAGATAAAAAATTGTATTTTATAAAAATGTCTAAAAGGTAAA
Downstream sequence
CACTTTAAAAGCAATGCTTcacaaacacaaatgagtacaggtaaaatgggaagtcgaaataagactggtggattgtatcaaagtcaatatcctggctctg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL215
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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