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TVIS44010717
Basic Information
VIS ID
TVIS44010717
Fusion event
HTLV-1-KCNN3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
154810004/154837528 (Hg38)
End
154810004/154837528 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
KCNN3
miRNAs that regulate target gene
hsa-mir-889-3p
;
hsa-mir-155-5p
;
hsa-mir-3152-3p
;
hsa-mir-6867-5p
;
hsa-mir-3182
;
hsa-mir-1237-3p
;
hsa-mir-92a-2-5p
;
hsa-mir-2053
;
hsa-mir-6857-5p
;
hsa-mir-4450
;
hsa-mir-8089
;
hsa-mir-4700-5p
;
hsa-mir-4667-5p
;
hsa-mir-6768-3p
;
hsa-mir-4753-5p
;
hsa-mir-1277-5p
;
hsa-mir-3942-3p
;
hsa-mir-5100
;
hsa-mir-190a-3p
;
hsa-mir-892c-5p
;
hsa-mir-5011-5p
;
hsa-mir-5003-3p
;
hsa-mir-335-3p
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-511-5p
;
hsa-mir-6830-3p
;
hsa-mir-29a-5p
;
hsa-mir-3920
;
hsa-mir-622
;
hsa-mir-4444
;
hsa-mir-4711-3p
;
hsa-mir-4724-3p
;
hsa-mir-501-5p
;
hsa-mir-6782-3p
;
hsa-mir-500b-5p
;
hsa-mir-362-5p
;
hsa-mir-2681-5p
;
hsa-mir-421
;
hsa-mir-1245b-3p
;
hsa-mir-3620-3p
;
hsa-mir-6865-3p
;
hsa-mir-4709-5p
;
hsa-mir-3613-3p
;
hsa-mir-548p
;
hsa-mir-181c-3p
;
hsa-mir-5683
;
hsa-mir-548c-3p
;
hsa-mir-203b-3p
;
hsa-mir-7158-3p
;
hsa-mir-378a-5p
;
hsa-mir-7111-3p
;
hsa-mir-6131
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-4680-5p
;
hsa-mir-4635
;
hsa-mir-3663-5p
;
hsa-mir-3653-5p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-3934-5p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-1273a
;
hsa-mir-1273g-3p
;
hsa-mir-3672
;
hsa-mir-4486
;
hsa-mir-4649-5p
;
hsa-mir-4793-3p
;
hsa-mir-4797-5p
;
hsa-mir-508-5p
;
hsa-mir-5586-3p
;
hsa-mir-661
;
hsa-mir-6729-5p
;
hsa-mir-6864-3p
;
hsa-mir-759
;
hsa-mir-7703
;
hsa-mir-873-3p
;
hsa-mir-939-3p
Nearest miRNA
hsa-mir-101-1/Upstream/643785; hsa-mir-1182/Downstream/138165;
Nearest TSS
ENST00000473358/Upstream/129302;
ENST00000604546/Downstream/22315;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/65140
,
chr1-CpG: 79/Downstream/98958
Upstream sequence
caccgcgcccagccTATCTACATGTAACAGCTGTGATCAAAGACCTAGGAAAACAGCCAACCCAGCCAACTCCTCCTCCTGGTTCCTCACCCTGGAGGAG
Downstream sequence
CTCTGGGCCCGAGAGCACAGAAGCTAGGAAGGCAGCAGAACGAGTGATGCTTATGGGGGAAAACCTGGCTTTCCACCCACAGCTGTTTCAAGGCGTCCTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL215
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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