Basic Information
VIS ID
TVIS44010732
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q15
Reference genome
GRCh37/hg19
Start
92699536/93363830 (Hg38)
End
92699536/93363830 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA5B ; FRA5D
Nearest miRNA
hsa-mir-10397/Upstream/3347110; hsa-mir-103a-1/Downstream/256866;
Nearest TSS
ENST00000502646/Upstream/295161; ENST00000512697/Downstream/58583;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1982717, chr5-CpG: 183/Downstream/206703
Nearby gene
NR2F1-AS1(No orient, 45526)
Upstream sequence
ATTTTTTTATGCCTGTGTCAGGACTGAAGAAATAAGCTATTCTACCTAAGATGACATGATTTGCCTCAAAGTAAATCCATTCTTGAGGCTGCTTGAAACG
Downstream sequence
TTATATGCTGCCAGTCCTGTTCCCAATTAATTTAACAAACTAGCTGATATTTTGCTTAAAAATATTTCAAGATGCTTATTTTGTTCTGTGTATACTGACT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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