Basic Information
VIS ID
TVIS44010763
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.2
Reference genome
GRCh37/hg19
Start
56208203/55742530 (Hg38)
End
56208203/55742530 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1B
Nearest miRNA
hsa-mir-12136/Upstream/516807; hsa-mir-101-1/Downstream/3990697;
Nearest TSS
ENST00000473358/Upstream/161469; ENST00000424357/Downstream/81277;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/526495, chr1-CpG: 47/Downstream/735025
Nearby gene
MIR4422(+516807) ;
Upstream sequence
CTTCAATTCAGTCTGGAAAGTGGGTAGCTAAGTTATGGTAGTATGTGCTTACATTTAGCATATCAACTCCCCAGCATCTCCTTGCACCCCAACTTTACCC
Downstream sequence
TTCATTCACAATTTTTAAAAAAGCATTGTGTTTGAGAAtgtctaccttactgcatttcaaactctttgtgggcaggaactacatcatgttcatgtgtaat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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