Basic Information
VIS ID
TVIS44010768
Fusion event
HTLV-1-IFI44 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
79118587/78652902 (Hg38)
End
79118587/78652902 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
IFI44
miRNAs that regulate target gene
hsa-mir-146a-5p ; hsa-mir-1-3p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1592700; hsa-mir-11399/Downstream/6480892;
Nearest TSS
ENST00000473358/Upstream/3044; ENST00000485662/Downstream/6417;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/161071, chr1-CpG: 33/Downstream/353694
Upstream sequence
tacatataattgttttttgaagaaaatacaatgaaattgctggatcatagggtatgtatatgttcattttcagttgacactgatgaaatttcccaacata
Downstream sequence
gttttatataaatttctagaactataagtagtgtacaaaggtctctgtcactccaaatctttttcagcattttgttttatttttagattatgtaactatt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate