VISDB Viral Integration Site DataBase

VIS ID

TVIS44010771

Fusion event

HTLV-1-TGFBR3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p22.1

Reference genome

Start

End

92206162/91740605 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-193b-3p ; hsa-mir-181a-5p ; hsa-mir-101-3p ; hsa-mir-6817-3p ; hsa-mir-6873-3p ; hsa-mir-7110-3p ; hsa-mir-541-5p ; hsa-mir-136-3p ; hsa-mir-382-3p ; hsa-mir-218-5p ; hsa-mir-513a-5p ; hsa-mir-369-5p ; hsa-mir-186-5p ; hsa-mir-3681-3p ; hsa-mir-27b-3p ; hsa-mir-216a-3p ; hsa-mir-27a-3p ; hsa-mir-128-3p ; hsa-mir-582-5p ; hsa-mir-202-3p ; hsa-mir-6715a-3p ; hsa-mir-144-3p ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-let-7d-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-4638-3p ; hsa-mir-3690 ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-330-3p ; hsa-mir-497-5p ; hsa-mir-195-5p ; hsa-mir-6838-5p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-424-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4753-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-130b-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183

Nearest miRNA

hsa-mir-101-1/Upstream/5382918; hsa-mir-11399/Downstream/2106227;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/193506, chr1-CpG: 123/Downstream/144751

Nearest cancer related gene

TGFBR3(TSG, No orient, 0)

Upstream sequence

aggcgtccaccatcaggcccggctaatttttgtatttttagtagagacagggtttcaccaggttgtccaggctggtcttgaactcctgacctcaggtgat

Downstream sequence

ccacctgcctcagccttccaaagtgctgggattataggcctgagccactgtgcccggtcacaggattactatttaacatgagatttgggcagggacatag