Basic Information
VIS ID
TVIS44010790
Fusion event
HTLV-1-MRPS21P2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
157831276/157861486 (Hg38)
End
157831276/157861486 (Hg38)
Orient
+
Location type
Intronic
Target gene
MRPS21P2
Nearest miRNA
hsa-mir-101-1/Upstream/925242; hsa-mir-1182/Downstream/2038493;
Nearest TSS
ENST00000473358/Upstream/19688; ENST00000359209/Downstream/36770;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/666141, chr1-CpG: 28/Downstream/117444
Nearby gene
CD5L(-19642) ;
Upstream sequence
ATAACATGGAAATGGCTCGCAAGATCAACTTCTTGATGCAAAAGAACTGGGTAGATCCGTGGCAGGGCTGCTGAGGCCTGTGGATGGGACACCCAGTATG
Downstream sequence
AAACCCTCATCCAAATTTGTCTCCATCTCTTTTCTTTCTACAATCCCATTTCCTATTACCGTTCTCTACAATAAACTCAATCACATGTTTGCAAGAAGGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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