Basic Information
VIS ID
TVIS44010800
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
172921183/172952043 (Hg38)
End
172921183/172952043 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1G
Nearest miRNA
hsa-mir-101-1/Upstream/807399; hsa-mir-1182/Downstream/3016327;
Nearest TSS
ENST00000473358/Upstream/45143; ENST00000460950/Downstream/98920;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/418638, chr1-CpG: 100/Downstream/524796
Nearby gene
TNFSF18(-89177) ;
Upstream sequence
ctttTAATGTctcacatggctggcaagttgatgctggctgttggctgggagctcagctgggctgtaggctggacatctttgtttctttccacttaggctg
Downstream sequence
atctacatgttgcgtaattgacacaaataatttagctgggttcaaaagtcagaatctcaagagataaaatgtagaagcagatggtttcatgacgcctaga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate