Basic Information
VIS ID
TVIS44010802
Fusion event
HTLV-1-LOC101928933 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
179923511/179954376 (Hg38)
End
179923511/179954376 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101928933
Nearest miRNA
hsa-mir-101-1/Upstream/150351; hsa-mir-1182/Downstream/483938;
Nearest TSS
ENST00000473358/Upstream/12580; ENST00000357434/Downstream/64;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/71140, chr1-CpG: 60/Downstream/205
Nearby gene
CEP350(+397) ;
Upstream sequence
TCATTAGATGCATGCTAAACAGAACTGTAACCCTCGCGAATAAAACGGCCACAGTGACAGCAGTGGGTAACGGCAGAGCTGCAACTACTCTGACAGGGGT
Downstream sequence
GACGACTTATTTGGACGACAGTTGGTGAAACATTGTAAACTCTCAGAAGCTGCCGTTTCCAGACTTTGAGTTCATTCTTGTCGAATCCCCAGCTTGTTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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