Basic Information
VIS ID
TVIS44010813
Fusion event
HTLV-1-LOC107985318 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q41
Reference genome
GRCh37/hg19
Start
222771718/222598376 (Hg38)
End
222771718/222598376 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107985318
Nearest miRNA
hsa-mir-101-1/Upstream/2397757; hsa-mir-1182/Downstream/1658664;
Nearest TSS
ENST00000473358/Upstream/8414; ENST00000470521/Downstream/19710;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/8448, chr1-CpG: 21/Downstream/19229
Nearby gene
TAF1A-AS1(No orient, 5743)
Upstream sequence
CTTTAAGGTGATGTTAGCTTTAAATGAAAAAAAAATTGTGAAGCAAAGTCACTTGAATCTAGAAAGACTTTTGTGTGAGACATCCTTTAAGGTGATGTTA
Downstream sequence
GCTTTAAATGAAAAAAAAAATTGTGAAGCAAAGTCACTTGAATCTAGAAAGACTTTTGAGTTTCTTTGGGTTTTATTGTTTTTGTTTTTACATTGATGTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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