VISDB Viral Integration Site DataBase

VIS ID

TVIS44010815

Fusion event

HTLV-1-PARP1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

q42.12

Reference genome

Start

End

226592935/226405234 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-21-5p ; hsa-mir-1301-3p ; hsa-mir-1225-3p ; hsa-mir-874-3p ; hsa-mir-93-3p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-339-5p ; hsa-mir-149-5p ; hsa-mir-128-3p ; hsa-mir-125b-5p ; hsa-mir-30b-5p ; hsa-mir-223-3p ; hsa-mir-708-5p ; hsa-mir-4799-5p ; hsa-mir-4696 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-577 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-6809-5p ; hsa-mir-3128 ; hsa-mir-31-5p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-7851-3p ; hsa-mir-619-3p ; hsa-mir-1229-5p ; hsa-mir-1225-5p ; hsa-mir-6079 ; hsa-mir-4775 ; hsa-mir-4536-5p ; hsa-mir-4451 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4650-3p ; hsa-mir-555 ; hsa-mir-6077 ; hsa-mir-3189-3p ; hsa-mir-6779-3p ; hsa-mir-4687-5p ; hsa-mir-129-2-3p ; hsa-mir-129-1-3p ; hsa-mir-7-5p ; hsa-mir-1303 ; hsa-mir-580-3p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-6770-5p ; hsa-mir-4670-3p ; hsa-mir-1253 ; hsa-mir-3123 ; hsa-mir-3925-5p ; hsa-mir-4475 ; hsa-mir-216b-5p ; hsa-mir-335-5p ; hsa-let-7a-5p

Nearest miRNA

hsa-mir-101-1/Upstream/483092; hsa-mir-1182/Downstream/1536356;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/95434, chr1-CpG: 82/Downstream/2398

Nearest cancer related gene

PARP1(TSG, No orient, 0)

Upstream sequence

TGGCCTTCACCAGCTCAGTCTACCAGACCAACTTTAAATTCTGAATTAAAACTCTGAATCCACCCTTAATCACCATTACATAAAAATCACAGTTACTTTT

Downstream sequence

AATAATAAAGAGTTTCTTTCACTATCAAGTATACCAAAGGAAAGCCCAGAATGTTGTTATTACTAttttttttttcagacagggtctgggtctgggtctg