Basic Information
VIS ID
TVIS44010816
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.13
Reference genome
GRCh37/hg19
Start
228771143/228635396 (Hg38)
End
228771143/228635396 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/173244; hsa-mir-1182/Downstream/2384432;
Nearest TSS
ENST00000473358/Upstream/147174; ENST00000366691/Downstream/99681;
Nearest CpG islands
chr1-CpG: 45/Target, None/Upstream, None/Downstream
Nearby gene
RNA5S8(-407) ; RNA5S13(+1698) ;
Upstream sequence
CTTGCCCCACCCACCCAGAGCCGTCAGGGCTGGCCGAAGGCGAACAGCCGGCCCAGCCGCGCCGGGCCTTTCTCTCACAACGCCCCCACCACGGTCGCTT
Downstream sequence
GTCCCGACCAAGACCCGGCCGGGGGGCAAGAGGGCGTGGGGTGTAGCGGGTCGGGGGGTGGCCCTGTTTTGCCCCGGGCTGGCACTAGAGGCGGCGGCCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate