Basic Information
VIS ID
TVIS44010821
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
GRCh37/hg19
Start
10104442/10062479 (Hg38)
End
10104442/10062479 (Hg38)
Orient
+
Location type
ncRNA_intronic
Nearest miRNA
hsa-mir-3155a/Upstream/3910202; hsa-mir-107/Downstream/2068281;
Nearest TSS
ENST00000439456/Upstream/3757; ENST00000420825/Downstream/304008;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/654233, chr10-CpG: 30/Downstream/203716
Upstream sequence
AAACCCACTAAAAATGGACAGATTTCTTTCTCAACTTGTTGAGGAGAGACATCATAGGATTCTTTCTATTATTTTAAGTTCCATCAAGTTTTTTCTCTCC
Downstream sequence
CCGGAGAGCTAATTTCTTACTGCACTCTTGAGTCATGACAGATAATTAGAAAATCTGGTCAGGCTTTTGCGGTGCCATATTTCTGCAAGTTTTGTATTGT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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