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VISDB
Viral Integration Site DataBase
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TVIS44010832
Basic Information
VIS ID
TVIS44010832
Fusion event
HTLV-1-MICU1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
74277058/72517300 (Hg38)
End
74277058/72517300 (Hg38)
Orient
-
Location type
Intronic
Target gene
MICU1
miRNAs that regulate target gene
hsa-mir-877-5p
Nearest miRNA
hsa-mir-1265/Upstream/726500; hsa-mir-107/Downstream/203729;
Nearest TSS
ENST00000439456/Upstream/8675;
ENST00000603649/Downstream/6636;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/162266
,
chr10-CpG: 42/Downstream/108409
Upstream sequence
GCTGCTTCTTAGCTGGTGTTTTAAAACCAAAGACCTGATtctaccatttgatccagcaatcccactactgggtatttactcaaaggaaaaggagtcatta
Downstream sequence
tacaaaaaagatacttgcatatgcatatttatagcagcacaattcacaactgcaaatacgtggaaccagcccaaatgcccatcaataaacaagtggataa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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