Basic Information
VIS ID
TVIS44010855
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
47980011/47958459 (Hg38)
End
47980011/47958459 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/557417; hsa-let-7a-2/Downstream/138323;
Nearest TSS
ENST00000527297/Upstream/109904; ENST00000526550/Downstream/22099;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/109655, chr11-CpG: 177/Downstream/21593
Nearby gene
PTPRJ(+22099) ;
Nearest cancer related gene
PTPRJ(TSG, +22099) ;
Upstream sequence
agcacctatcaaagtgcctagtatgaagtcgagtgctttatttttattttttCTGCTAAATTAAATTCTCACTGATGTAGTTGGCTCTCATCCATCATTG
Downstream sequence
CTGGCCTTTTAGTTCTCCCTGGTTCTGGCTGCATCTCTGTTTCTTCAGCTTCTGTTGTCCACAGCCCTAGCCTGCCTTGTCTTAATCTATCTCTGGTCAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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