Basic Information
VIS ID
TVIS44010898
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
77029332/76635552 (Hg38)
End
77029332/76635552 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Upstream/7050729; hsa-mir-1178/Downstream/2783705;
Nearest TSS
ENST00000382841/Upstream/73258; ENST00000551407/Downstream/128036;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/75502, chr12-CpG: 77/Downstream/128186
Nearby gene
OSBPL8(-75743) ;
Upstream sequence
tgtagaaacggtctcactctcttgcccaggctgatctcaaacacttgttcccaagatcttcctaccttggcctcccgaagtgctggaattacaggcataa
Downstream sequence
gccaccacacctggccTTAATGACATAATTTACACTAAATGTTTTGAGAGGGAGGGAGAGAAAAGCTGAAAGCCAGAATGCTAactggaagaaatatatt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate