Basic Information
VIS ID
TVIS44010907
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
96516458/96122680 (Hg38)
End
96516458/96122680 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Upstream/812696; hsa-mir-1178/Downstream/1369229;
Nearest TSS
ENST00000382841/Upstream/79160; ENST00000547249/Downstream/49446;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/86949, chr12-CpG: 133/Downstream/71381
Nearby gene
ELK3(+71702) ;
Nearest cancer related gene
ELK3(OG, +71702) ;
Upstream sequence
ctgcagcttcaaactcctgggctcaagagatcctcccgcctcagcctccagagtagttggggctacaagcatgcaccaccacacccggcCAATCAAACAG
Downstream sequence
TGTCTTTGACAGCAGCCGGTCCAGCTCAGCCAGCTCCTTGCCACTCCATGTTCCGGCTAGTCCTGGGGTGGCCATGAAACCTGGCTGTAGTAGCCTCTGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate