Basic Information
VIS ID
TVIS44010932
Fusion event
HTLV-1-MIR548F5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
36366452/35792315 (Hg38)
End
36366452/35792315 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
MIR548F5
Nearest miRNA
hsa-mir-2276/Upstream/11629811; hsa-mir-1267/Downstream/3871719;
Nearest TSS
ENST00000623511/Upstream/94588; ENST00000379848/Downstream/1164;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/313333, chr13-CpG: 75/Downstream/338588
Upstream sequence
AGGGTTCAATCGAGAAACACGAAATGCAAACAGTACGAGGGTGTGTATGCATGCATTCGTACCATTTGCAAATTCTGGAACCTCATATCAAATACTCAGT
Downstream sequence
AACCCAGATCTGGGATTGGTGGCATCAAACAGATCACTTGTTTATCTTCAGTTTTTTTTTAGAGCTCTCGCGCAACCAAAAAAGAAAAAAAGGAAAGAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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