Basic Information
VIS ID
TVIS44010944
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
53583649/53009514 (Hg38)
End
53583649/53009514 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-15a/Upstream/199374; hsa-mir-1267/Downstream/1302458;
Nearest TSS
ENST00000623511/Upstream/160873; ENST00000219022/Downstream/19245;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/157654, chr13-CpG: 217/Downstream/190615
Nearby gene
OLFM4(+19227) ;
Nearest cancer related gene
OLFM4(TSG, +19227) ;
Upstream sequence
GAGACACTCTATCTCCTTTTGTATGCATTTTGTAAAATTCAACATTTATGAAACAAGCGGAGTCTTACAAAAACATCTGAGGGTTAAATCTAGCTTTGGC
Downstream sequence
TCGCAAGTTGTAGATTCCTAAAAAATATAATGTTGGGCATTTTATTTATTAGCTATTGTTTGAGGAGTCCAGATGGGATGACCAAGGCCTAGTTTTTATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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